Simvastatin   Ist ein Cholesterin-Senker, der von diversen Generika-Herstellern produziert wird und eine Reduktion des Auftretens neuer Läsionen zur Folge haben soll.   20. 5. 2010; PubMed.gov; Simvastatin treatment in patients with RRMS receiving interferon beta 1a: a doubleblind randomized controlled trial http://www.ncbi.nlm.nih.gov/pubmed/20488825   8. 7. 2011; PubMed.gov; Simvastatin as add-on therapy to interferon beta-1a for relapsing-remitting multiple sclerosis (SIMCOMBIN study): a placebo-controlled randomised phase 4 trial. http://www.ncbi.nlm.nih.gov/pubmed/21742556  „INTERPRETATION: We found no beneficial effect of simvastatin as add-on therapy to interferon beta-1a. Although unlikely, we can not exclude that combination of other statins with other disease-modifying drugs still could be beneficial.“   15. 9. 2011; PubMed.gov; Simvastatin improves final visual outcome in acute optic neuritis: a randomized study. http://www.ncbi.nlm.nih.gov/pubmed/21921071 „Conclusion: This study provides Class I evidence that simvastatin 80 mg daily is well tolerated and possibly effective in patients with acute ON (optic neuritis).“   Oct. 2011; msj; Impact of rituximab on relapse rate and disability in neuromyelitis optica http://msj.sagepub.com/content/17/10/1225.abstract „Median relapse rate declined significantly from 1.87 relapses/patient per year to 0.0 relapses/patient per year. Kurtzke Expanded Disability Status Scale (EDSS) scores stabilized or improved in all patients. Use of rituximab is associated with a significant reduction in relapses and disability in patents with NMO (Neuromyelitis optica).“     „Wer nicht zur Wahl geht, stärkt die, gegen die er protestieren will“ Zur Medikamenten-Übersicht   http://georgieff.at/